Dosimetric study of radioadaptive response of zebrafish embryos using PADC-film substrates
نویسندگان
چکیده
We found the alpha-particle priming dose which could effectively induce in vivo radioadaptive response in the embryos of the zebrafish, Danio rerio, to be 4.8e48 mGy, through the apoptotic signals scored in the embryos at 24 h post fertilization. Specially fabricated thin polyallyldiglycol carbonate (PADC) films were used as support substrates for the dechorionated embryos. During irradiation, alpha particles passed through the PADC films to hit the zebrafish embryos, and the alpha-particle tracks were revealed in the films through chemical etching. By determining the number of alpha-particle tracks that coincided with the effective areas of the embryos, the alpha-particle doses were found. 2011 Elsevier Ltd. All rights reserved.
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